May 15, 2025

Rethinking Treatment: Why It’s Not One Drug for One Disease Anymore w/ Sebastian Denison

Rethinking Treatment: Why It’s Not One Drug for One Disease Anymore w/ Sebastian Denison

If you think pharmacy is still a “one drug for one disease” model, think again. People don’t get sick in a single silo, so why would we treat them that way?

That’s why pharmacists today are unleashing the power of repurposing a drug at a lower dosage to get a benefit.

Sebastian Denison, a compounding pharmacist on the frontlines of this shift, is the perfect person to have this conversation with!

Using medications like low-dose Naltrexone, we’re able to tap into multiple mechanisms at once, reduce inflammation, calm an overactive immune system, and support whole-body healing!

For too long, modern medicine has focused on treating isolated symptoms, prescribing one drug for one receptor, one diagnosis, one problem.

But the body doesn’t work that way. Everything is connected.

This new model of pharmacy looks at the entire person and provides multifaceted solutions.

In this episode, we explore why it’s time to stop treating disease in isolation and how forward-thinking pharmacists are using multi-targeted, low-dose therapies to reach far beyond a single symptom or receptor site.

 

Things You’ll Learn In This Episode 

Why “one drug, one receptor” is an outdated myth

The days of single-function prescriptions are over. How are today’s compounds designed to work across systems, supporting your body’s natural healing intelligence?

Modulation not suppression 

Inflammation in the body is like a dial, you have to find the right balance. How do we pull away from dysfunctional inflammation and get back to healthy inflammation? 

The problem with extremes (even healthy ones)

In excess, even the healthiest activities can be detrimental to your health and lead to chronic inflammation. How does living in extremes lead to a stressed-out body?