LDN • Compounded

Low dose naltrexone, compounded the way your prescriber wrote it.

Naltrexone is FDA-approved at 50mg. The doses your provider may prescribe for autoimmune, chronic pain, or inflammation conditions (typically 0.5–4.5mg) don't exist commercially. They have to be compounded — and that's what we do.

  • Custom strengths from 0.5mg through 6mg
  • Capsule or topical cream, your prescriber's call
  • Slow-release options available on request
  • Same or next business day turnaround
Compounded low dose naltrexone in the Magnolia Pharmacy lab
Steve Hoffart, PharmD
Compounded right here in Magnolia, Texas — formulated for you, not the masses.
How LDN works

A different mechanism at a different dose.

At low doses, naltrexone briefly blocks opioid receptors at night. The body responds by upregulating endogenous endorphin and enkephalin production over the following hours.

Many prescribers and researchers believe this immune-modulating effect is what may help patients with autoimmune and inflammatory conditions feel better — without the sedation or dependence risk of stronger medications.

Conditions prescribers commonly use LDN for

LDN is being explored across a wide range of inflammatory and autoimmune conditions. Talk to your prescriber about whether it might support your situation.

  • Autoimmune Conditions

    Hashimoto's, lupus, rheumatoid arthritis, psoriasis, MS.

  • Chronic Pain & Fibromyalgia

    Widespread pain, tender points, post-exertional flares.

  • Long COVID & Chronic Fatigue

    Persistent fatigue, brain fog, post-exertional malaise.

  • Mood & Cognition

    Depression, anxiety, and cognitive symptoms tied to inflammation.

  • IBS & Crohn's

    Inflammatory bowel symptoms and gut-immune dysregulation.

  • Sleep & Recovery

    Poor recovery, restless sleep, daytime fatigue.

Steve Hoffart, PharmD, Founder of Magnolia Pharmacy
The Trusted Pharmacist

Steve Hoffart, PharmD trains prescribers nationwide on compounded LDN.

Every formulation that leaves our lab is one we'd give our own family.

— Steve Hoffart, PharmD · Founder

Steve has spent the last decade educating providers on LDN protocols, titration strategies, and the practical reality of compounding it accurately. When your script lands in our lab, it's getting weighed and verified by people who know exactly what it's for.

20+
Years compounding for Houston families
1 of few
Sterile-cleanroom 503A pharmacies in TX
100%
Pharmacist-reviewed formulations
Meet the team

From script to first dose — in days, not weeks.

  1. Step 1

    Send us your script

    Your prescriber faxes, e-prescribes, or sends through our portal.

  2. Step 2

    We verify the dose

    Pharmacist reviews titration plan, flags interactions, and confirms strength.

  3. Step 3

    We compound it

    USP 795 compounding in our on-site Magnolia lab — typically same business day.

  4. Step 4

    Ship or pick up

    Texas-wide shipping or local pickup. Refills auto-tracked in our portal.

Frequently Asked Questions

What is low dose naltrexone (LDN)?

Naltrexone at standard doses (50mg) is used for substance dependence. At low doses (typically 0.5–4.5mg), it acts very differently — modulating the immune system and reducing inflammation. LDN is being used by prescribers for autoimmune, chronic pain, and inflammatory conditions.

Why does LDN need to be compounded?

Commercial naltrexone only comes in 50mg tablets. To get a low dose, the medication has to be compounded into a smaller, accurate strength — typically as capsules or a topical cream. This is exactly the kind of work our compounding lab is built for.

What's the typical titration schedule?

Many prescribers start patients at 0.5–1.5mg at bedtime and titrate up over 4–8 weeks toward 3–4.5mg, monitoring response. Your prescriber will design the schedule for you — we'll compound each strength along the way.

Are there side effects?

LDN is generally well-tolerated at low doses. The most common early side effect is vivid dreams or sleep disruption, which usually resolves within 1–2 weeks. Some people prefer dosing in the morning instead.

Do I need a prescription for LDN?

Yes. LDN is prescription-only. We work with your existing prescriber, or we can help connect you with providers in our network who specialize in LDN protocols.

How fast is your turnaround?

Most LDN scripts are compounded the same or next business day. We ship throughout Texas and beyond.

Ready when you are

Need LDN compounded? We're ready.

Whether you're a patient looking for a pharmacy that knows LDN, or a prescriber who needs a reliable compounding partner — let's talk.

Local pickup in Magnolia, TX · Shipping across Texas & most states.

  • PCAB-Accredited Compounding Pharmacy
  • USP 795 & 797 Sterile Compliant
  • PCCA 2022 Pharmacist of the Year
  • Serving Houston Since 2002

Compounded medications: This content is for informational purposes only and does not constitute medical advice. Compounded medications are prepared based on a prescription from a licensed healthcare provider and are not FDA-approved. Consult your healthcare provider before starting any new treatment.

Dietary supplements: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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